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Claritin Clarinex

Claritin, the non-sedating antihistamine used mainly for seasonal hay fever and year round nasal allergies is now sold over-the-counter. Schering-Plough, the original manufacturer is now touting its metabolic derivative, Clarinex, since losing its patent.

Once Schering’s most successful product, with yearly sales exceeding 3 billion dollars, the company has replaced Claritin with Clarinex (Claritin’s main active metabolic product) while the generics have creeped into the marketplace.

Both products have many forms. All are taken orally. One form melts on the tongue and does not need swallowing. Claritin is FDA approved from age 2 while Clarinex is restricted to 12 year olds and above.

As with other non-sedating antihistamines, these products are no more effective than traditional antihistamines. Their value however is significant. Because they do not cross the blood – brain barrier, there is minimal if any central nervous system side effects, that is essentially no drowsiness, slowed reaction time, and clumsiness.

Clinical studies caution the public of the potential hazards of taking traditional antihistamines (Benadryl, Chlortrimeton, Pyribenzamine, and their derivatives) Side effects are evident in using machinery 24 hours later. Some have suggested freeway accidents are more commonly the result of taking antihistamines than from imbibing alcohol.

Bill Ziering

Rx365  A Year of Tips for the Successful Medical Practice


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